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Analysis of UHMWPE particle shape effects on bioactivity from the physical viewpoint of phagocytosis process

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摘要

Biophysical principles were applied to calculate the maximum number of ultra-high molecular weight polyethylene (UHMWPE) particles that can be phagocytosed for various size and shapes of particles. It was assumed that the particle has an ellipsoidal shape with one longer and two equal shorter axes. It was found that, with the same total particle volume, elongated particles gather more macrophage cells in the phagocytosis process. It was also found that smaller particles within the phagocytosable range induce stronger bioactivity than large particles that cannot be engulfed by the macrophage cells.

原文English
主出版物標題Transactions - 7th World Biomaterials Congress
頁面1328
頁數1
出版狀態Published - 2004
事件Transactions - 7th World Biomaterials Congress - Sydney, Australia
持續時間: 17 5月 200421 5月 2004

出版系列

名字Transactions - 7th World Biomaterials Congress

Conference

ConferenceTransactions - 7th World Biomaterials Congress
國家/地區Australia
城市Sydney
期間17/05/0421/05/04

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