Abstract
A new surface-plasmon-resonance (SPR) waveguide biosensor with the capability of bipolarization wavelength interrogation is presented. In the conventional SPR biosensors, only the transverse magnetic (TM)-polarized lightwave can couple with the surface plasma wave. The proposed SPR biosensor can make both the TM- and the transverse electric (TE)-polarized lightwave to produce the SPR. Therefore, two kinds of biomaterials can be separately detected by the signals from the TM- and the TE-polarized modes, and the number of detectable materials in a single chip can be doubled. Human serum albumin is coated on the device to sense the concentration of beta-blocker. Experimental results show that the concentration of beta-blocker is related to the SPR wavelength shift at a rate of 0.08 and 0.027 nm/ppm for the TM- and the TE-polarized modes, respectively.
| Original language | English |
|---|---|
| Pages (from-to) | 1715-1717 |
| Number of pages | 3 |
| Journal | IEEE Photonics Technology Letters |
| Volume | 16 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 2004 |
Bibliographical note
Funding Information:Manuscript received February 2, 2004; revised March 11, 2004. This work was supported by National Science Council, Taipei, Taiwan, R.O.C., under Contract NSC 92-2215-E-027-001. T.-J. Wang and C.-W. Tu are with the Institute of Electro-Optical Engineering, National Taipei University of Technology, Taipei 10651, Taiwan, R.O.C. (e-mail: [email protected]). F.-K. Liu and H.-L. Chen are with the National Nano Device Laboratories, Hsinchu 30050, Taiwan, R.O.C. Digital Object Identifier 10.1109/LPT.2004.828376
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