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Study of bone restoration Ca-Si-Zn complex

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this research, the purpose is to carry out the in vitro study of the plasticity hybrid complex. The main components of the material are tricalcium silicate (C3S, Ca3SiO5) and collagen. In vitro studies, including cell toxicity test (MTT), flowcytometry detection and alkaline phosphatase test (ALP) were carried out to evaluate the biocompatibility of the materials and soaking mediums. Results showed that soaking mediums of different amounts of materials didn't affect cell growth harmfully. Moreover, the soaking mediums would stimulate the osteoblast and trigger the biomineralization processes leading to higher secretion of ALP during cultivation. The results in this research showed that the biocompatibility of our hybrid complex for future applications.

Original languageEnglish
Title of host publicationBioceramics 25
PublisherTrans Tech Publications Ltd
Pages427-430
Number of pages4
ISBN (Print)9783037858998
DOIs
StatePublished - 2014
Event25th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2013 - Bucharest, Romania
Duration: 7 Nov 201310 Nov 2013

Publication series

NameKey Engineering Materials
Volume587
ISSN (Print)1013-9826
ISSN (Electronic)1662-9795

Conference

Conference25th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2013
Country/TerritoryRomania
CityBucharest
Period7/11/1310/11/13

Keywords

  • Collagen
  • In vitro study
  • Plasticity hybrid complex
  • Tricalcium silicate

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