Phylogenetic analysis of trichomonade xylosyltransferases

Kuo Yuan Hwa; Hsing Hsang Hung; Chen Hsing Chen

doi:10.1109/FBIT.2007.109

Phylogenetic analysis of trichomonade xylosyltransferases

Kuo Yuan Hwa
, Hsing Hsang Hung
, Chen Hsing Chen

Department of Molecular Science and Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Scopus citations

Abstract

Our goal is to search for xylosyltransferase genes from the T. vaginalis EST genome database by bioinformatics approaches. First, we have constructed a theoretical model of conserved xylosyltransferase sequences based on a Hidden Markov Models (HMM) built from known xylosyltransferases sequences. Eight candidate sequences of xylosyltransferase are detected in T. vaginalis genome. We have also confirmed the results by blasting through NCBI's non-redundant protein database. To analyze which family of xylosyltransferase these sequences belongs to, we have constructed an unrooted dendrogram of xylosyltransferease protein family, based on distance-matrix method. The result suggests that the T. vaginalis xylosyltransferase sequences are more closely related to beta-1,2-xylosyltransferases, but not to O-linked xylosyltransferase. All our in silico results are consistent with the structural data of T. vaginalis N-linked glycans.

Original language	English
Title of host publication	Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007
Pages	299-304
Number of pages	6
DOIs	https://doi.org/10.1109/FBIT.2007.109
State	Published - 2007
Event	Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007 - Jeju Island, Korea, Republic of Duration: 11 Oct 2007 → 13 Oct 2007

Publication series

Name	Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007

Conference

Conference	Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007
Country/Territory	Korea, Republic of
City	Jeju Island
Period	11/10/07 → 13/10/07

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10.1109/FBIT.2007.109

Cite this

Hwa, K. Y., Hung, H. H., & Chen, C. H. (2007). Phylogenetic analysis of trichomonade xylosyltransferases. In Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007 (pp. 299-304). Article 4524123 (Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007). https://doi.org/10.1109/FBIT.2007.109

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title = "Phylogenetic analysis of trichomonade xylosyltransferases",

abstract = "Our goal is to search for xylosyltransferase genes from the T. vaginalis EST genome database by bioinformatics approaches. First, we have constructed a theoretical model of conserved xylosyltransferase sequences based on a Hidden Markov Models (HMM) built from known xylosyltransferases sequences. Eight candidate sequences of xylosyltransferase are detected in T. vaginalis genome. We have also confirmed the results by blasting through NCBI's non-redundant protein database. To analyze which family of xylosyltransferase these sequences belongs to, we have constructed an unrooted dendrogram of xylosyltransferease protein family, based on distance-matrix method. The result suggests that the T. vaginalis xylosyltransferase sequences are more closely related to beta-1,2-xylosyltransferases, but not to O-linked xylosyltransferase. All our in silico results are consistent with the structural data of T. vaginalis N-linked glycans.",

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Hwa, KY, Hung, HH & Chen, CH 2007, Phylogenetic analysis of trichomonade xylosyltransferases. in Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007., 4524123, Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007, pp. 299-304, Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007, Jeju Island, Korea, Republic of, 11/10/07. https://doi.org/10.1109/FBIT.2007.109

Phylogenetic analysis of trichomonade xylosyltransferases. / Hwa, Kuo Yuan; Hung, Hsing Hsang; Chen, Chen Hsing.
Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007. 2007. p. 299-304 4524123 (Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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Phylogenetic analysis of trichomonade xylosyltransferases

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