TY - GEN
T1 - Phylogenetic analysis of HA proteins of influenza virus H1N1 reveal new insight on virus pandemic
AU - Hwa, Kuo Yuan
PY - 2009
Y1 - 2009
N2 - The pandemic (H1N1) 2009 virus is life-threatening for some patients. Analysis of virus genome sequences has provided biomedical scientists new insight in understanding host-virus interaction. We have addressed the questions if HA protein is in related to virulence of viruses. To test the hypothesis, we have focuses our analysis on the protein of hemagglutinant (HA), a protein , from the virus isolated three regions with similar living standard, popuin HongKong (death rate: 2.57 per million), Taiwan (death rate: 0.74 per million) and Japan (death rate: 0.14 per million). Our results suggest that in the human population, the virus H1N1 have isolated several time both in Taiwan and Japan, as early as in 2002 and with a dominant occurrence in 2009. However, through phylogenetic analysis, the The recent outbreak of H1N1 has different sequence origin than the previous ones. And, between the years of 2002-2008, the dominant virus stain is H3N2. The results suggest that the general population in Taiwan might not have the immunity against the new virus.
AB - The pandemic (H1N1) 2009 virus is life-threatening for some patients. Analysis of virus genome sequences has provided biomedical scientists new insight in understanding host-virus interaction. We have addressed the questions if HA protein is in related to virulence of viruses. To test the hypothesis, we have focuses our analysis on the protein of hemagglutinant (HA), a protein , from the virus isolated three regions with similar living standard, popuin HongKong (death rate: 2.57 per million), Taiwan (death rate: 0.74 per million) and Japan (death rate: 0.14 per million). Our results suggest that in the human population, the virus H1N1 have isolated several time both in Taiwan and Japan, as early as in 2002 and with a dominant occurrence in 2009. However, through phylogenetic analysis, the The recent outbreak of H1N1 has different sequence origin than the previous ones. And, between the years of 2002-2008, the dominant virus stain is H3N2. The results suggest that the general population in Taiwan might not have the immunity against the new virus.
KW - Death Rate
KW - Neuramidase
KW - Phylogentic Analysis
KW - Protein Sequence
UR - https://www.scopus.com/pages/publications/78249267275
U2 - 10.1007/978-3-642-10616-3_20
DO - 10.1007/978-3-642-10616-3_20
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AN - SCOPUS:78249267275
SN - 3642106153
SN - 9783642106156
T3 - Communications in Computer and Information Science
SP - 146
EP - 150
BT - Bio-Science and Bio-Technology - International Conference, BSBT 2009. Held as Part of the Future Generation Information Technology Conference, FGIT 2009, Proceedings
T2 - International Conference on Bio-Science and Bio-Technology, BSBT 2009. Held as Part of the Future Generation Information Technology Conference, FGIT 2009
Y2 - 10 December 2009 through 12 December 2009
ER -