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Biofabrication of biopolymer and biocomposite scaffolds for bone tissue engineering

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

The aims of this study were to fabricate biopolymer and biocomposite scaffolds for bone tissue engineering by an air pressure-aided deposition system. A thermosensitive mPEG-PCL-mPEG triblock copolymer was synthesized as a biopolymer material. Biocomposite material was composed of synthesized biopolymer and hydroxyapatite (HA) with a mean diameter of 100 μm. The weight ratio of HA added to the synthesized biopolymer was 0.5. The experimental results show that the average compressive strength of biocomposite scaffolds with mean pore size of 410μm (porosity 81%) is 18.38 MPa which is two times stronger than that of biopolymer scaffolds.

Original languageEnglish
Title of host publicationEmerging Technology in Precision Engineering XIV
PublisherTrans Tech Publications Ltd
Pages374-379
Number of pages6
ISBN (Print)9783037855096
DOIs
StatePublished - 2012
Event14th International Conference on Precision Engineering, ICPE 2012 - Hyogo, Japan
Duration: 8 Nov 201210 Nov 2012

Publication series

NameKey Engineering Materials
Volume523-524
ISSN (Print)1013-9826
ISSN (Electronic)1662-9795

Conference

Conference14th International Conference on Precision Engineering, ICPE 2012
Country/TerritoryJapan
CityHyogo
Period8/11/1210/11/12

Keywords

  • Deposition
  • Hydroxyapatite
  • Poly(ethylene glycol) (PEG)
  • Poly(ε- Caprolactone)
  • Scaffold

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